Evidence-Based Medicine these 7 years : time for the editor to go on permanent sabbatical
Grading evidence from test accuracy studies : what makes it challenging compared with the grading of effectiveness studies?
Rating the certainty in evidence in the absence of a single estimate of effect
How good is the evidence to support primary care practice?
Similar prostate cancer and all-cause mortality in men with localised prostate cancer undergoing surgery or radiation therapy versus active monitoring at 10 years of follow-up
Team-based primary care with integrated mental health is associated with higher quality of care, lower usage and lower payments received by the delivery system
Early invasive strategy in patients with non-ST segment elevation acute coronary syndrome delays death or MI by 18 months
A clinical risk score to predict the incidence of postpartum venous thromboembolism
Close contact casting may result in similar outcomes compared with plate fixation for unstable ankle fractures in patients over 60 years old
Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration
Abdominal electroacupuncture demonstrates an increase in complete spontaneous bowel movements
Intensive blood pressure lowering provides no additional benefits and results in more adverse events
High-intensity exercise offers no additional benefit to moderate-intensity exercise in reducing liver fat in patients with non-alcoholic fatty liver disease
Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood
Oral antibiotics are as effective as intravenous antibiotics for postdischarge treatment of complicated pneumonia in children
Conduct and reporting of a vertebroplasty trial warrants critical examination
Resumption of anticoagulation after major bleeding decreases the risk of stroke in patients with atrial fibrillation
In patients with intracerebral haemorrhage and concomitant atrial fibrillation, optimal timing of reinitiating anticoagulants may be 7–8 weeks after ICH
Stroke rates vary substantially across cohorts of patients with atrial fibrillation
Caesarean section is associated with offspring obesity in childhood and young adulthood
Among opioid-naive patients receiving opioids, more intensive opioid prescribing in the first month is associated with transition to long-term opioid use
In children 7 years of age, prenatal antidepressant exposure is not associated with increased risk of poor behavioural outcomes after adjusting for maternal factors including antenatal mood
Urine concentration should be taken into account when interpreting pyuria in infants
Criticisms of the VAPOUR trial in a recent commentary are unsubstantiated and incorrect