What is the most effective lipid-lowering therapy for children with dyslipidemia?

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Evidence-Based AnswerIn children with familial hypercholesterolemia, statins are effective for lowering total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C). Diets or dietary supplements do not appear to significantly lower lipid levels. There is limited evidence that ezetimibe is effective and safe in lowering TC, LDL-C, and triglycerides (TG) (SOR: C, disease-oriented evidence).

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