Blood count parameters as a marker for metabolic syndrome in older adults


    loading  Checking for direct PDF access through Ovid

Abstract

Background and aimBlood count parameters are associated with the metabolic syndrome (MS). However, few studies have evaluated the precision of blood count components to identify MS in older adults. We evaluated the accuracy of blood count components as a screening method and a marker of MS in older adults.Methods and resultsA cross-sectional study with 203 older adults of both sexes was conducted. The following variables were used: MS as defined by harmonized criteria, hemoglobin, hematocrit, leukocytes and platelets. Area under the receiver operating characteristic (ROC) curve, sensitivity (sens), specificity (spec) and logistic regression were adjusted for age and sex. Leukocyte count showed the highest Youden's index value for MS screening, with an optimal cut-off point of 7.514 103/mm3 (sens: 66.7%; spec: 72.0%) for men and 5.626 103/mm3 (sens: 73.1%; spec: 42.4%) for women. Older adults with leukocyte count higher than these cut-off points presented a 2.4 times greater chance of developing MS.ConclusionLeukocyte count can be used as a screening indicator to identify individuals with a higher risk of developing MS. Older adults with high leukocyte count and no associated chronic diseases should receive attention, as they are individuals with a potential risk for MS.HighlightsEvaluation of blood count components of metabolic syndrome prediction in older adultsThe leukocyte count can be used as a screening indicator to identify individuals with a higher risk of metabolic syndrome.Leukocyte count presented a relation with metabolic syndrome components (TG, glycemia and DBP).Early use of indicators in older adults allows a better clinical evaluation.Effective intervention to prevent and treat risks related to metabolic syndrome.

    loading  Loading Related Articles