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The 14th International Celiac Disease Symposium (ICDS) took place in Oslo, Norway, on 20–22 June 2011, with 530 registered attendees, including clinicians, researchers, sponsors and patients. The 3-day symposium included an international scientific section, and a concurrent clinical forum. It provided a comprehensive overview of the basic, clinical and translational aspects of celiac disease in two keynote lectures, 11 introductory presentations, ten lectures from experts, 227 poster presentations and 38 oral presentations. It highlighted the importance of integrating the knowledge from clinics, genetic studies and immunological studies to better understand celiac disease.