The Effect of Latanoprost on Accommodation in Young Patients with Ocular Hypertension

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PurposeTo determine whether topical latanoprost 0.005% had an effect on accommodative capacity after 1 month of treatment in young patients with ocular hypertension.Patients and MethodsFifteen patients (9 men and 6 women, aged 20–40 years) with ocular hypertension were instructed to instill the drug to their right eye for 1 month; the left eye received no medication and served as control. Near point of accommodation, refraction, and intraocular pressure (IOP) were determined after 1 month of treatment.ResultsAfter 1 month of treatment with latanoprost, the mean IOP was reduced by 22.8% (5.8 mm Hg) in the treated eye and 1.86% (0.47 mm Hg) in the untreated control eye. No significant changes in refraction or near point of accommodation were observed in the treated or untreated eye.ConclusionShort-term treatment with latanoprost 0.005% does not effect refraction or accommodation in young patients with ocular hypertension.

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