IDDF2018-ABS-0264 Prevalence of anxiety, depression and quality of life in among school going adolescent with irritable bowel syndrome

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Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorders (FGIDs) that affects different aspects of life and patients experienced depression and anxiety more than others. There have been few Asian studies regarding anxiety and depression associated IBS. The aim of this study was to evaluate the frequency, magnitude and importance of anxiety and depression in among school going adolescent with IBS in Jaipur city, India.


A Cross-sectional survey of students of four classes from 9th to 12th studying in government schools in Jaipur city, India. Ten government schools in Jaipur were randomly selected through lottery method. In each school, for each of the four classes, a section was randomly selected again by the lottery method. Forty students were selected from each school reaching a sample size of 470. This clinical trial study was done in IBS patients (with mild-to-moderate symptoms) divided into two case and control groups. All participants were asked to complete self-administered questionnaires: one addressing symptom severity and the hospital anxiety and depression scale (HADS). The patients were also asked to complete the IBS-specific quality of life (IBS-QOL) questionnaire.


Anxiety and depression were observed in 32.1% and 34.5% of IBS patients, respectively, and in 26.6% and 17.2% of healthy subjects, respectively (p<0.05 for both) in school adolescent. Both anxiety and depression were associated with self-reported symptom severity (p<0.05 and p<0.05, respectively). As determined by multivariate analysis, symptom severity was the most important factor in the prediction of anxiety and depression. Self-reported symptom severity and depression were clearly and independently associated with the overall IBS-QOL score.


Anxiety and depression were frequently observed in school going adolescent in Jaipur city IBS patients and were related to the severity of their symptoms and the impairment of the patient‘s QOL. Our data suggest that assessing anxiety and depression is important when evaluating IBS patients. There is a need for early and effective identification of anxiety, depression that can prevent many psychiatric disorders at their nascent stage with irritable bowel syndrome.

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