IDDF2018-ABS-0147 Efficacy and safety of endoscopic retrograde cholangiopancreatography in nonagenarians: a comparative study

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Abstract

Background

Little information is available on the long-term outcome of endoscopic retrograde cholangiopancreatography (ERCP) for pancreatobiliary diseases in nonagenarians (≥90 years). This study was to evaluate the efficacy and the safety of of ERCP in the treatment of patients 90 years of age and older.

Methods

Consecutive nonagenarian patients who underwent therapeutic ERCP between May 2005 and January 2017 at a tertiary-care centre were retrospectively reviewed. One hundred and fifty-five patients aged 90 years and older were identified (Group A). Matched by gender and ratio 1:2, 310 patients under 65 years were assigned to control group (Group B). Clinical features, endoscopic findings, interventions, long-term results of ERCP for a mean follow-up of 12 months were assessed and compared between the two groups.

Results

Group A had a higher incidence of concomitant diseases, acute cholangitis, and acute cholecystitis, as compared to group B (p<0.05). There was no significant difference in the technical success rate and procedure time between the two groups. The rate of post-ERCP pancreatitis was significantly less in the group A compared to the group B (p<0.05). The occurrence of haemorrhage, perforation, and other complications was not statistically different among the two groups. The mortality directly related to the ERCP procedure was zero.

Conclusions

ERCP is safe and effective for the management of pancreatobiliary diseases in patients aged 90 years or older.

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