ASSA14-04-03 The Clinical Characteristics and Coronary Angiography Features of Patients with Apical Hypertrophic Cardiomyopathy

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Abstract

Objective

To analyse the clinical characteristics and coronary angiography features of patients with Apical Hypertrophic Cardiomyopathy (AHCM).

Methods

The baseline features, clinical characteristics and coronary angiography features were retrospectively analysed.

Results

25.9% of all the Hypertrophic Cardiomyopathy (HCM) patients were diagnosed with AHCM patients (99 cases vs 382 cases). The mean age of males were younger than famales onset (52.0 ± 11.5 years vs 58.4 ± 10.5 years, p = 0.009). The major clinical characteristics were chest pain, dyspnea, angina and palpitation with 74.7%, 54.5%, 50.5% and 28.3% respectively (74, 54, 50 and 28 cases). Complications were hypertention, diabetes mellitus and hyperlipemia with 35.4%,12.1% and 4.0% respectively (35, 12 and 4 cases). 12-lead electrocardiogram (ECG) revealed sinus rhythm and left ventricular hypertrophy voltage on 72 patients (72.7%), and the gaint negative T waves were presented on 80 patients (80.8%) (maximum depth 2.4 mv). On echocardiography, mean apical wall thickness, interventricular septum thickness and left ventricular outflow tract gradient were 19 ± 8 mm, 16 ± 5 mm and 40 ± 49 mmHg respectively. Left ventricular angiography revealed left ventricular apex thickening in different degrees (maximum thickness 40 mm). A majority of patients (98.0%) revealed the “Spades” except for 2 cases described as similar “Spades”and “Ballet foot” respectively.

Conclusions

The AHCM, with a higher morbidity, generally have a benign prognosis. Left ventricular angiography should be performed when [1] electrocardiography and echocardiography are failed to diagnose.

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