ASSA14-04-03 The Clinical Characteristics and Coronary Angiography Features of Patients with Apical Hypertrophic Cardiomyopathy

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ObjectiveTo analyse the clinical characteristics and coronary angiography features of patients with Apical Hypertrophic Cardiomyopathy (AHCM).MethodsThe baseline features, clinical characteristics and coronary angiography features were retrospectively analysed.Results25.9% of all the Hypertrophic Cardiomyopathy (HCM) patients were diagnosed with AHCM patients (99 cases vs 382 cases). The mean age of males were younger than famales onset (52.0 ± 11.5 years vs 58.4 ± 10.5 years, p = 0.009). The major clinical characteristics were chest pain, dyspnea, angina and palpitation with 74.7%, 54.5%, 50.5% and 28.3% respectively (74, 54, 50 and 28 cases). Complications were hypertention, diabetes mellitus and hyperlipemia with 35.4%,12.1% and 4.0% respectively (35, 12 and 4 cases). 12-lead electrocardiogram (ECG) revealed sinus rhythm and left ventricular hypertrophy voltage on 72 patients (72.7%), and the gaint negative T waves were presented on 80 patients (80.8%) (maximum depth 2.4 mv). On echocardiography, mean apical wall thickness, interventricular septum thickness and left ventricular outflow tract gradient were 19 ± 8 mm, 16 ± 5 mm and 40 ± 49 mmHg respectively. Left ventricular angiography revealed left ventricular apex thickening in different degrees (maximum thickness 40 mm). A majority of patients (98.0%) revealed the “Spades” except for 2 cases described as similar “Spades”and “Ballet foot” respectively.ConclusionsThe AHCM, with a higher morbidity, generally have a benign prognosis. Left ventricular angiography should be performed when [1] electrocardiography and echocardiography are failed to diagnose.

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