Migraine Headaches and Preeclampsia: An Epidemiologic Review

    loading  Checking for direct PDF access through Ovid

Abstract

Objective

To summarize and evaluate available empirical research on the relationship between migraines and gestational hypertension or preeclampsia and to provide direction for future research in this area.

Background

Migraines affect a substantial proportion of reproductive-aged women and have been associated with cardiovascular risk factors and ischemic disease in this population. Preeclampsia is a vascular disorder of pregnancy, also linked to adverse cardiovascular outcomes.

Methods

Publications were identified by a MEDLINE search using keywords “migraine,”“preeclampsia,” and “gestational hypertension,” and by examination of the reference lists of identified articles.

Results

The literature review yielded 10 studies addressing the association between migraines and preeclampsia or gestational hypertension. Of the 10 studies, 8 reported a positive association between the syndromes.

Conclusions

Available evidence suggests that migraines and preeclampsia may reflect an underlying predisposition toward ischemic injury. More rigorous epidemiologic research is warranted, after consideration of several important methodologic issues.

Related Topics

    loading  Loading Related Articles