Associations of estimated residential soil arsenic and lead concentrations and community-level environmental measures with mother–child health conditions in South Carolina

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We undertook a community-level aggregate analysis in South Carolina, USA, to examine associations between mother–child conditions from a Medicaid cohort of pregnant women and their children using spatially interpolated arsenic (As) and lead (Pb) concentrations in three geographic case areas and a control area. Weeks of gestation at birth was significantly negatively correlated with higher estimated As (rs=−0.28, p=0.01) and Pb (rs=−0.26, p=0.02) concentrations in one case area. Higher estimated Pb concentrations were consistently positively associated with frequency of black mothers (all p<0.02) and negatively associated with frequency of white mothers (all p<0.01), suggesting a racial disparity with respect to Pb.

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