Since 1961, at the Oak Ridge Y-12 Plant, operated by UCC-ND for the United States Department of Energy, about 2200 employees per year have been routinely monitored by bioassay and in vivo techniques for internal exposure of uranium. In order to help control exposures, 49 of those employees (upon showing elevated results in either of the monitoring programs) were restricted from working with uranium for periods of six months or longer. A summary of the monitoring experience on these employees during the periods of removal is presented, and typical or illustrative cases are discussed. Four previously reported anomalous cases in which the monitoring results remained elevated for more than four years are reviewed and brought up to date. It is demonstrated that the removal of employees from uranium work generally results in a quick return of their monitoring results to minimum levels.