Interhemispheric Relationships in Opiate-Addicted Patients during the Withdrawal and Early Post-withdrawal Periods

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A study was made of the functional asymmetry of the brain hemispheres during the withdrawal and early post-withdrawal periods in 69 heroin-addicted male patients. Heroin withdrawal was associated with a reorganization of interhemispheric relationships. A more favorable time course of the normalization of the functions studied was observed in subjects with a dominant left hemisphere. A correlation was found between the individual asymmetry profile and the mean daily dose of heroin.

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