Supportive effects of Rosa damascene essential oil on epididymal sperm quality following long-term administration of copper sulfate in mice

    loading  Checking for direct PDF access through Ovid

Abstract

Background

This study aimed to evaluate the supportive effects of Rosa damascene essential oil on epididymal sperm quality following long-term administration of copper sulfate in mice.

Materials and methods

The study included four different groups of six mice as follows: group Cu, which received 0.1 ml copper sulfate solution at a dose of 100 mg/kg, group R, which received 0.1 ml R. damascene essential oil at a dose of 1 mg/kg, treatment group (T), which received copper sulfate solution (100 mg/kg) and treatment with R. damascene essential oil (1 mg/kg), and control group (C), which received the same volume of normal saline. The supplements were gavaged in all animals every other day during the experimental period. All animals were killed 6 weeks after the beginning of the experiment.

Results

Sperm concentration, motility, and viability in group Cu were significantly decreased after 6 weeks and improved in the treatment group in comparison with the Cu group.

Conclusion

Administration of the essential oil of R. damascene can protect the testis and epididymal sperm from the adverse effects of copper poisoning in mice.

Related Topics

    loading  Loading Related Articles