Introduction Whether use of blood pressure lowering medications (BPLMs) is associated with presence and severity of coronary artery disease (CAD) is unknown. The aim of this study was to examine the relationship between BPLMs and coronary artery calcium score (CACS) as a marker of CAD in patients with acute chest pain.
Methods In this cross-sectional study, 1030 consecutive patients without reported history of CAD who presented with acute chest pain were included. CACS by non-contrast multi-detector computed tomography scan, BPLMs profiles prior to the visit were collected. Patients were categorized by presence and severity of CACS, number and classes of BPLMs used.
Results The population with mean age of 54±13 years consisted of 60.6% (624 of 1030) patients with zero CACS, 21.7%(223 of 1030) with mild calcification(0
Conclusion Use of blood pressure lowering medications is associated with presence and severity of coronary artery disease in patients with acute chest pain.