Captopril treatment in elderly hypertensive patients: efficacy and tolerability


    loading  Checking for direct PDF access through Ovid

Abstract

Ninety-five elderly (>70 years) hypertensive patients were treated for 3 months with 25-100 mg captopril daily. The mean blood pressure decrease was from 179/101 to 155/87 mmHg (P<0.001). The heart rate did not change. The drug was generally well tolerated (patients taking <100mg captopril or captopril + chlorthalidone reported side effects) and there was no change in the biochemical parameters (glucose, uric acid, cholesterol, high density lipoprotein-cholesterol, triglycerides, apoproteins, blood urea nitrogen, creatinine, serum electrolytes). Our open study indicates that captopril is a safe and effective antihypertensive agent in elderly patients. However, some caution is necessary when high doses of captopril (100mg/day) are used

    loading  Loading Related Articles