P-099 Impact of Inflammatory Bowel Disease on Sexual Function of Patients in a Mexican Population

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Abstract

Background:

Inflammatory Bowel Disease (IBD) is composed of 2 main disease categories: Crohn's Disease (CD) and Ulcerative Colitis (UC). Medical management will always have as its main objective the control of digestive and systemic symptoms of the disease. In addition, since the late 80s several authors have studied quality of life (QoL) related to health. Although sexuality is an important factor in the patient's quality of life, this aspect is not taken into account in the QoL questionnaires and the issue of sexuality has been relegated to clinical investigation in IBD patients.

Objective:

Determine the impact of IBD on sexual function of patients attending the consultation of a tertiary referral hospital in Mexico City.

Methods:

Observational, descriptive, transversal, primary source study. We included sexually active patients, 18 to 70 years old, who attended to IBD consultation in “Centro Médico Nacional 20 de Noviembre” between June and August of 2016. All patients have a confirmed diagnosis of UC or CD for at least 6 months. To evaluate fundamental aspects that might affect sexuality of patients with IBD we associated the severity of clinical activity with sexual dysfunction, quality of life, sex and age. To establish the presence or absence of sexual dysfunction we used the “Changes in Sexual Functioning Questionnaire” (CSFQ) applying versions for men and women. The severity of IBD clinical activity was measured by “Harvey-Bradshaw severity Index” for Crohn's disease and “Modified Truelove-Witts severity Index” for Ulcerative Colitis. We measured the patient's quality of life using the 9 questions version of “IBD Quality of Life Questionnaire” (IBDQ-9). Data was tabulated in a Windows Microsoft Excel 2013 database, then exported to SPSS 19.0 version. Chi square and t student test was used to determine statistical significance of the proposed variable crossings.

Results:

Forty patients were included, 26 with UC and 14 with CD, mean age was 49.2 years; 65% of them had sexual dysfunction. Sexual desire was altered in 60% of individuals, sexual interest in 90%, pleasure 70%, excitement 82.5% and orgasm 77.5%. The proportion of subjects with sexual dysfunction was higher in those patients with active disease when compared with those with inactive disease (72.2% versus 59.1%, P = 0.469). Sexual dysfunction prevalence was greater in women than in men, being present in 41.2% of men and 82.6% of women (P = 0.007). Older participants had a higher proportion of subjects with sexual dysfunction (P = 0.509). It was observed that higher levels of QoL were perceived in individuals with lower proportions of sexual dysfunction. (P = 0.627).

Conclusions:

Sexual dysfunction is an important factor in patients with inflammatory bowel disease and should be an explored aspect on medical control visits in order to provide a multidisciplinary approach to the problem, especially in women and patients with active disease.

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