Severe Thrombocytopenia in the Third Trimester of Pregnancy Subsequent to Seasonal Non-H1N1 Influenza A Virus Infection

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Viral infections can induce hematological disorders including immune thrombocytopenic purpura (ITP). Influenza-induced ITP is infrequent and has never been reported in a third-trimester pregnant woman.


A previously healthy pregnant woman in the third trimester presented with non-H1N1 Influenza A and a platelet count of 0. She was diagnosed with ITP and treated with intravenous immunoglobulin and oseltamivir. Her platelet count returned to normal by day 8, and she delivered vaginally a normal infant who had no evidence of thrombocytopenia or Influenza.


Influenza A can induce secondary ITP in pregnancy, and the standard treatment for both ITP and Influenza A is effective.

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