Bordetella bronchiseptica is a well-described pathogen classically causing respiratory infections in household pets. We describe a case of postsurgical meningitis in an adult patient. A 49-year -old man with a recently resected glioblastoma developed altered mental status approximately 2 weeks after surgery and was found to have B bronchiseptica meningitis. B bronchiseptica is a very rare cause of meningitis. It has only been described twice before in the literature, both in pediatric patients. It should be considered in patients with household pets. It can be a particularly virulent organism given its ability to form biofilms. In our case, the patient failed initial treatment with 2 weeks of meropenem and required re-treatment.