Treatment of : A Case ReportKlebsiella pneumoniae: A Case Report Carbapenemase–Producing : A Case ReportKlebsiella pneumoniae: A Case Report Bacteremia With Meropenem, Colistin, and Ceftazidime-Avibactam: A Case Report

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Abstract

Ceftazidime-avibactam is a novel combination antimicrobial agent consisting of a broad-spectrum cephalosporin, ceftazidime, and a non–β-lactam β-lactamase inhibitor, avibactam. This agent has demonstrated activity against resistant gram-negative bacteria, including Klebsiella pneumoniae carbapenemase–producing organisms; however, it is US Food and Drug Administration approved for use in urinary tract and intra-abdominal infections only. We present a case of successful treatment of K. pneumoniae carbapenemase–producing K. pneumoniae bacteremia with a combination of meropenem and colistin followed by ceftazidime-avibactam and colistin.

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