Vancomycin Combined with Piperacillin-Tazobactam Increases the Risk for Acute Kidney Injury

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A retrospective cohort study found an increased risk of acute kidney injury for patients who received vancomycin in combination with piperacillin-tazobactam compared to those who received vancomycin plus cefepime (hazard ratio = 4.27; 95% confidence interval, 2.73-6.68).

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