The Highway to Hell: A RIP Kinase-Directed Shortcut to Inflammatory Cytokine Production

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Abstract

RIPK1 and RIPK3 are well-known signaling traffic cops in innate immunity. In this issue of Immunity, Degterev and colleagues show that when they blow the whistle on bacterial infection, they quickly point a white-gloved hand down the express route to inflammatory cytokine production.

RIPK1 and RIPK3 are well-known signaling traffic cops in innate immunity. Degterev and colleagues show that when they blow the whistle on bacterial infection, they quickly point a white-gloved hand down the express route to inflammatory cytokine production.

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