Superficial Immunity: Antimicrobial Responses Are More Than Skin Deep

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Abstract

The skin barrier is essential for host defense, but how the skin provides protection when the barrier is breached is not well understood. In this issue of Immunity, Gallo and colleagues report that keratinocytes integrate signals from antimicrobial peptides via MAVS signaling to amplify their antiviral immune response.

The skin barrier is essential for host defense, but how the skin provides protection when the barrier is breached is not well understood. Gallo and colleagues report that keratinocytes integrate signals from antimicrobial peptides via MAVS signaling to amplify their antiviral immune response.

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