Antigen-Primed CD8+ T Cells Call DCs for Back Up

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Encounters between naive T lymphocytes and dendritic cells (DCs) bearing adequate co-stimulatory signals are rare. In this issue of Immunity, Brewitz et al. (2017) show that chemokines secreted by CD8+ T cells recruit myeloid and plasmacytoid DCs that in turn boost CD8+ T cell activation.

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