Bach2: An Instrument of Heterogeneity for Long-Term Protection

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Abstract

Generation of functionally diverse effector and memory killer T cells is essential for immediate and long-term protective immunity.Herndler-Brandstetter et al. (2018)report thatBach2promotes functional plasticity of effector T cells and the transition into the long-term memory compartment by regulating the expression of the inhibitory receptor KLRG1.

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