A Hen in the Wolf Den: A Pathobiont Tale

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Abstract

Disruption of the gut microbiota is thought to contribute to disease onset in individuals with a genetic predisposition to autoimmunity. In a recent issue ofScience, Manfredo Vieira et al. (2018)identify translocation of the gut commensalEnterococcus gallinaruminto the liver as a trigger for the autoimmune disease systemic lupus erythematous.

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