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The Ministry of Health has a policy to establish ‘Organizational Measures’ as a key strategy to prevent road accidents. They are therefore study the format of guidelines.To study and develop management system in accordance to the context of the hospital.A study developed by the research process routines (R2R) in Kranuan Crown Prince Hospital, Khon Kaen based on the theoretical concept of POSDCoRB Management Process which has been conducted since April 1, 2015 to July 31, 2017. The key factors were the management of government cars and ambulance, compliance with traffic laws and related laws, and behavior of the officers in terms of helmet use. In addition, they need to collect data from evidence of registration/insurance/Inspection/Operation System of the drivers and report the performance of the concerned agents. GPS tracking/surveillance systems analysis of the data was conducted.1) A copy of the notice to the hospital in April 2015 or about 1 month after the announcement. 2) Khon Kaen Provincial Health Office issued a notice on the development of ambulance safety standards on January 15, 2016, or 10 months after the announcement of the Ministry. 3) Kranuan Crown Prince Hospital has transformed the policy into practice and has appointed a team of committee. The results of monitoring and evaluation during the past year were as follows: (3.1) Working Group operated under ‘Management Process’. (POSDCoRB) for each individual step (3.2) Ambulance meets the criteria of all emergency medical institutions (100%). All ambulances are covered by Voluntary Insurance level 1. All official cars have safety belts. In terms of a driver, there was one driver out of 9 did not pass Safety Ambulance Training. (3.3) GPS surveillance also found ambulance cars driving exceed the speed limit from April 1 to June 30, 2017 for 20 times (April: 14, May: 5, and June: 1) from 537 referrals (164, 215, 158) (accounted for 3.7% in average or 8.5%, 2.3% and 0.8%, respectively) and (3.4) Officers wearing helmet showed 100 percent during the preparation of the assessment. However, after the assessment was as low as 38% and the group that wear helmet less in percentage was the service personnel who worked off-duty and the staff who stay at the hospital hospice. However, it was found that the rate of helmet usage was high in the working group during working hours (08.00–16.00). (3.5) during the past year, there was no appreciation for good people or penalty/punishment. However, there were warnings 2 times, and officials have clarified the guidelines to the drivers 3 times.Organizational measures should be taken to ensure the safety of personnel and be good role models for the public. It is necessary to urgently urge all hospitals to take measures in the organizations and expand to other agencies especially local authorities that have to take care of local rescuers.