Evaluation of Semiautomated Internal Carotid Artery Stenosis Quantification from 3-Dimensional Contrast-Enhanced Magnetic Resonance Angiograms

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Rationale and Objectives:

The performance of a semiautomatic technique for internal carotid artery (ICA) stenosis quantification of the internal carotid artery in contrast-enhanced magnetic resonance angiography was evaluated.

Materials and Methods:

The degree of stenosis of 52 ICAs was quantified by measuring the cross-sectional area along the center lumen line. This was performed both by 3 independent observers and the semiautomated method. The degree of stenosis was defined as the amount of cross-sectional lumen reduction.


Agreement between the method and observers was good (weighted-kappa, κw = 0.89). Reproducibility of measurements of the semiautomated technique was better (κw = 0.97) than that of the observers (κw = 0.76), and the evaluated technique was considerably less time-consuming.


Because the user interaction is limited, this technique can be used to replace an expert observer in 3-dimensional stenosis quantification of the ICA at CE-MRA in clinical practice.

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