Fatal Cardiac Dysrhythmia Following a Bupropion Overdose in an Adolescent


    loading  Checking for direct PDF access through Ovid

Abstract

Bupropion is an antidepressant that is currently used in the treatment of depression, attention deficit–hyperactive disorder, and bipolar diseases; as well as an aid in smoking cessation. Although its neurotoxicity and propensity to cause seizures are well described in the literature, bupropion has been suggested to be a more desirable anti-depressant when compared to the tricyclic antidepressants due to its lack of cardiotoxicity. To date, there are limited reports with regard to cardiac toxicity. The authors present a 15-year-old boy who developed torsades de pointes and cardiac arrest as a result of a bupropion overdose. Other reports of potential cardiac toxicity related to bupropion are reviewed.

    loading  Loading Related Articles