Prevention of Relapse in Depression: Antidepressants or Mindfulness-based Cognitive Therapy?

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SYNOPSIS: Maintenance antidepressants or mindfulness-based cognitive therapy aimed at tapering or discontinuing antidepressants are both effective interventions for prevention of recurrent depression.SOURCE: Kuyken W, et al. Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): A randomised controlled trial. Lancet 2015;386:63-73.“Good morning, Pooh Bear,” said Eeyore gloomily. “If it is a good morning,” he said. “Which I doubt,” said he. “Why, what's the matter?”“Nothing, Pooh Bear, nothing. We can't all, and some of us don't. That's all there is to it.”“Can't all what?” said Pooh, rubbing his nose.“Gaiety. Song-and-dance. Here we go round the mulberry bush.”From Winnie the Pooh by A.A. Milne

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