Adhesive Contrast Material in the Diagnosis of Experimental Gastrointestinal Bleeding


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Abstract

Hypaque 60, Renografin 76, and Adhesive Contrast Material (ACM) were tested in superior mesenteric arteriography prior to and after the production of an intraluminal bleeding in the jejunum or ileum of 10 dogs. Blood pressure and blood flow in a segmental branch of the superior mesenteric artery, central aortic blood pressure, and serial radiography were used as parameters. It was concluded that:Production of the upper intestinal bleeding resulted in long persisting vasospasm of the supplying segmental artery. It is suggested that this should be considered in patients with G.I. bleeding where extravasation has not been demonstrated.ACM provided approximately two times longer visualization of the mesenteric arterial bed as compared to the Hypaque 60 or Renografin 76, when used in equal doses. The capillary phase and venous opacification were less dense when ACM (rather than H60 or R76) were used.In seven dogs, ACM selectively persisted in the terminal arterial branches supplying the damaged segments. Three of the dogs showed the intraluminal puddling. Three dogs showed only selective persistence of ACM, and one dog did not show either of these. The phenomenon of this persistence was related to the locally decreased blood flow and suggests its potential in clinical use.

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