Inhibition of Adenosine Triphosphatase and Carbonic Anhydrase by Contrast Media

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In vitro inhibition of adenosine triphosphatase and carbonic anhydrase by several radiographic contrast media and other compounds was measured. The concentrations required for 50% inhibition were, in general, similar to those obtained for other enzymes. The effect of methylglucamine could not be determined for either enzyme because of interference with the assays.

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