Novel vaccine works a treat for ragweed allergies

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The novel ragweed allergen 1018 ISS conjugate [Tolamba] is effective in reducing the allergic response in patients with seasonal ragweed allergies, according to a phase II/III trial presented at the 62nd Annual Meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI) [Miami Beach, Florida, US; March 2006]. The randomised, double-blind, multicentre trial, conducted over two ragweed seasons and involving more than 450 patients with seasonal ragweed allergies, showed that a single 6-week course of Tolamba prior to the first ragweed season significantly improved the patient-assessed total nasal symptom score (TNSS) from baseline, compared with placebo, during both allergen seasons.

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