How do you solve a problem like transfusion-related acute lung injury?

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The last 20 years have seen substantial international efforts to minimize the incidence and risk of transfusion-related acute lung injury (TRALI). Nevertheless, TRALI remains a real morbidity and mortality risk to transfusion recipients.


This review discusses the current knowledge on antibody- and non-antibody-mediated TRALI, as well as current and potential mitigation strategies.

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