In search of an optimum dose escalation for narrowband UVB phototherapy: Is it time to quit 20% increments?

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Abstract

Objectives

Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy.

Study patients

The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III.

Results

Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalations, whereas response rates and time to response did not significantly differ.

Limitations

The study was limited by its retrospective nature.

Conclusion

A 5% or 10% incremental regimen may have similar therapeutic efficacy.

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