G-101 Non-neutralizing antibody activities: The good, bad and indifferent

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Abstract

Several studies have been aimed at categorizing the effect of non-neutralizing antibodies in preventing HIV infection. Some of these studies will be reviewed, and recently published and unpublished data will be described that underscore the complexity of humoral immune responses to HIV envelope glycoproteins. A particular focus will be placed on the role of non-neutralizing antibodies in enhancing infection and the potential role of phagocytosis in preventing infection.

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