Oral Cryotherapy for Preventing Oral Mucositis in Patients Receiving Cancer Treatment

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Abstract

Clinical Question

In patients receiving treatment for cancer, does oral cryotherapy prevent oral mucositis?

Bottom Line

Oral cryotherapy is effective for the prevention of oral mucositis in adults receiving fluorouracil-based chemotherapy for solid cancers, and for the prevention of severe oral mucositis in adults receiving high-dose melphalan-based chemotherapy before hematopoietic stem cell transplantation (HSCT).

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