Tracheobronchopathia Osteochondroplastica Associated with Calcification of Falx Cerebri and Rhinobronchial Syndrome with Nasal Polyposis

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Tracheobronchopathia Osteochondroplastica is a rare disease characterized by metaplastic proliferation of osseus tissue in the anterolateral portion of trachea and bronchi, often concomitant to chronic inflammation of the respiratory tract. Before the advent of bronchoscopy and imaging techniques, it was usually diagnosed at autopsy, and its origin is unknown. A 31-year-old nonsmoking woman with tracheobronchopathia Osteochondroplastica and anomalies of the nose, paranasal sinuses, and falx cerebri is described. A congenital predisposition to hyperplastic-metaplastic changes in the connective tissue on dysontogenetic basis is suggested.

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