We report a 40-year-old woman with no history of smoking or radiation therapy who was tracheostomized in infancy for a juvenile larngeal papillomatosis. The tracheostomy was closed and she was asymptomatic for many years, until she developed progressive dysphonia and hemoptysis. A bronchos- copy yielded a laryngotracheal papillomatosis that had metastasized to the superior segment of the left lower lobe. Laryngotracheal lesions were treated successfully with Nd:YAG laser but papillomalosis of the superior segment of the left lower lobe only responded partially to this treatment. A lobectomy of the left lower lobe was performed. Pathology demonstrated squamous cell carcinoma complicating a pulmonary papillomalosis.