Endotracheal Small-Cell Carcinoma of the Lung in a Patient with AIDS

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We describe a patient with acquired immunodeficiency syndrome (AIDS) in whom respiratory distress due to endotracheal obstruction was the presenting feature of a small-cell carcinoma of the lung. The unusual aspects of this patient included the histologic findings of small-cell carcinoma of the lung in AIDS, the endotracheal location of the lesion, and the rapid and full endoscopically confirmed response to radiation therapy. This report of bronchogenic carcinoma in an AIDS patient raises the question of the relationship between human immunodeficiency virus infection and cancer of the lung.

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