Thirty infants weighing less than 1,500 g at birth and requiring assisted ventilation were studied by computed tomography (CT) as soon as possible after birth and at intervals thereafter. Hemorrhage was frequently detected within the first 48 hr of birth. Two infants had normal scans initially but developed intraventricular hemorrhage later. One infant had subependymal hemorrhage that later ruptured into the ventricles. Six deaths were due directly to intracranial hemorrhages. Hydrocephalus developed in seven and atrophy in two survivors. There was poor correlation between CT scan and clinical evidence of intracranial hemorrhage.