Dialysis machines are artificial kidneys that perform some kidney functions for patients who have renal failure and are used to clean the blood and balance its constituents. The machine maintenance and calibration are extremely important in the evaluation of adequacy of hemodialysis and in assessing dialysis session performance. The objectives of this study are to change the degree of concentration of chemical elements in water treatment during a year time in the Kassala state, to decrease the risk of water contamination with respect to the kidney failure of patients in water treatment unit, and to find the best effective solutions in case of any changes in the chemical concentration of the water. The study has been done during the period from January 2014 to March 2015 in Kassala Hospital’s Department of Renal Diseases. The study author concluded that water element concentration rates changed significantly during the year. This conclusion requires an attention to investigate the reasons behind these changes and the effects of these changes on the dialysis treatments. One way to do so is to monitor the contents of water treatment unit periodically and to make sure that each part is efficiently working. This will be done by taking samples to check it regularly for accuracy, corresponding to the required needs.