Portable suction machines are widely implemented in both clinical and home care settings. Two identical new machines were tested at 3 different levels of pressure settings operating at intermittent intervals. The study uncovered that noncalibrated portable suction triggers an additional 17% higher suction pressure than the actual most efficient and desired pressure setting. There are statistically significant differences between the calibrated suction machine and noncalibrated suction machine at 3 levels of settings: 80, 100, and 120 mm Hg. This emphasizes the need for fundamental safety redesign of clinical calibration measures for clinical engineering.