Taking a bite: endocytosis in the maintenance of the slit diaphragm

    loading  Checking for direct PDF access through Ovid


In the kidney, the slit diaphragm joins adjacent podocytes, forming an epithelial barrier that filters plasma into the urinary space, yet retains blood cells and proteins within the circulation. In this issue of the JCI, Soda et al. have identified clathrin-mediated endocytosis as a central mechanism by which the function and structural integrity of the slit diaphragm are maintained.

Related Topics

    loading  Loading Related Articles