A Bullous Flare of a Hyperkeratotic Affair: A Case Report

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Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling familial benign chronic pemphigus or Hailey-Hailey disease.


The objective of this report is to describe an uncommon presentation of Darier's disease, which has been infrequently described in the literature.


The authors present a case of bullous flare of long-standing Darier's disease.


Darier's disease may assume several atypical morphologies, including vesiculo-bullous lesions.

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