Academic medicine's landscape is dynamically adjusting. The changes are accelerating and these alterations are impacting both the faculty workforce as a whole and individual faculty members. This article reviews workforce and institutional changes within academic medicine and supports the need for faculty members to adapt to this changing landscape. Resources to maintain an understanding of these ongoing changes are reviewed. A faculty life-cycle model is proposed as a context for developing a personal action plan. Career management steps are suggested to facilitate career productivity and satisfaction. Finally, we propose that psychologists, being human behavior experts, are well positioned to contribute within the transformation of academic medicine.