Test-Retest Reliability of Maximal and Submaximal Gas Exchange Variables in Patients With Coronary Artery Disease

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Abstract

PURPOSE:

Gas exchange variables derived from cardiopulmonary exercise tests (CPETs) need to be reliable for evaluating interventions and clinical decision making. Whereas peak oxygen uptake (

PURPOSE:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM1/v/2017-08-02T192518Z/r/image-png

PURPOSE:

O2) has shown to be a highly reliable parameter in patients with coronary artery disease (CAD), little is known about the reproducibility of these parameters in patients with CAD. Therefore, the purpose of this study was to confirm the reliability of peak

PURPOSE:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM2/v/2017-08-02T192518Z/r/image-png

PURPOSE:

O2 and to investigate the reliability of submaximal CPET variables in patients with CAD.

METHODS:

Eighty-five patients with CAD (57.6 ± 8.5 years; 79 males) performed 2 CPETs within 10 days before starting a rehabilitation program. Reliability of peak and submaximal exercise variables was assessed by using intraclass correlation coefficients (ICC), coefficients of variation, Pearson correlation coefficients, paired t tests, and Bland-Altman plots.

RESULTS:

Maximal and submaximal exercise parameters showed adequate reliability. Overall, there was a good correlation across both testing occasions (r = 0.63-0.95; P < .05 for all). Peak

RESULTS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM3/v/2017-08-02T192518Z/r/image-png

RESULTS:

O2 (ICC, 0.95; 95% CI, 0.92-0.97) demonstrated excellent reliability. Of the submaximal exercise variables, oxygen uptake efficiency slope (OUES) was as reliable as peak

RESULTS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM4/v/2017-08-02T192518Z/r/image-png

RESULTS:

O2 (ICC, 0.97; 95% CI, 0.95-0.98). The ventilation/carbon dioxide production (

RESULTS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM5/v/2017-08-02T192518Z/r/image-png

RESULTS:

E/

RESULTS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM6/v/2017-08-02T192518Z/r/image-png

RESULTS:

CO2) slope showed very good test-retest reliability (ICC, 0.87; 95% CI, 0.80-0.91) and the

RESULTS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM7/v/2017-08-02T192518Z/r/image-png

RESULTS:

O2/work rate slope showed good reliability (ICC, 0.76; 95% CI, 0.64-0.85).

CONCLUSIONS:

Both peak

CONCLUSIONS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM8/v/2017-08-02T192518Z/r/image-png

CONCLUSIONS:

O2 and OUES show excellent test-retest reliability. Accordingly, in the case of no or unreliable peak

CONCLUSIONS:

JOURNAL/jcprh/04.02/01273116-201607000-00006/math_6MM9/v/2017-08-02T192518Z/r/image-png

CONCLUSIONS:

O2 data, we suggest using OUES to evaluate cardiorespiratory fitness in patients with CAD.

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