We reported 1 case of primary Sjögren syndrome in a child. The patient complained recurrent submandibular inflammation for more than 2 years without apparent sicca presentations, and Schirmer test resulted negative. However, ultrasound showed hypoechoic areas in the gland, laboratory tests reported the positivity of Sjögren’s syndrome A antigen and Sjögren’s syndrome B antigen, and biopsy presented periductal lymphocytic infiltration. Therefore, a diagnosis of primary Sjögren syndrome was conducted. Treatment of it required a multidisciplinary team.