The present study aims to discuss the value and the effect of resection of suprasellar meningioma through the interhemispheric approach. Twenty-nine cases of patients with suprasellar meningioma diagnosed through enhanced magnetic resonance imaging scans and postoperative histopathologic examination underwent resection of tumors (the largest diameter ranged from 3 cm to 6 cm) by the microsurgical technique of small bone window (about 5 cm × 6 cm) through the interhemispheric approach. Among all cases, 25 (86%) (Simpson I, II) were of total resection of tumors and 4 were of subtotal resection of tumors. Moreover, along all cases, 19 were of improved vision and view, 2 of postoperative diabetes insipidus, and 1 of electrolyte imbalance. No operative death occurred. The small bone window interhemispheric approach can be used to expose tumors, lightly stretch brain tissues, reduce the incidence of complications, and improve the total resection rate of tumors of patients with sellae meningiomas growing forward, upward, and into the sella.