Tooth Loss May Be More Frequent in Older People With a Genetic Predisposition Towards Dementia

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Abstract

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION

Tooth loss, dementia and neuropathology in the Nun Study.

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION

Stein, P. S., M. Desrosiers, S. J. Donegan, J. F. Yepes and R. J. Kryscio (2007).

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION

J Am Dent Assoc 138(10):1314-22; quiz 1381-2.

LEVEL OF EVIDENCE

Level 2 (Limited-quality, patient-oriented evidence)

STRENGTH OF RECOMMENDATION GRADE

Not applicable

PURPOSE/QUESTION

The authors wished to identify any statistical relationships between the number of remaining teeth and both the prevalence at baseline and autopsy and the incidence of dementia and in a cohort of older nuns over a 12 year period.

SOURCE OF FUNDING

National Institute of Aging (US) with additional funding from NIH and two research foundations

TYPE OF STUDY/DESIGN

Observational retrospective cohort study plus cross-sectional analysis

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