Sample size was 170 with approximately 45% female; the study was conducted in the Karlsburg area, Germany; dates of recruitment were December 1997 to December 2000 and respiratory allergies were present in 22 subjects.Key Exposure/Study Factor
The primary exposure was periodontal attachment loss, which was categorized in different days.Main Outcome Measure
Respiratory allergies were present if subjects reported a positive history for either hay fever, allergy, house dust mite (HDM) or asthma.Main Results
The subjects were categorized in 4 groups according to the quartiles of the percentage of surfaces that exceeded 3-mm attachment loss (AL) as follows: healthy periodontal conditions: 0% to 7.6% of sites with AL greater than 3mm, mild: 7.7% to 27.0% of sites with AL greater than 3 mm, moderate: 27.1% to 54.2% of sites with AL greater than 3mm, and severe: more than 54.2% of sites with AL greater than 3mm. The full model showed that individuals with severe AL (odds ratio [OR] 0.06; 95% confidence interval [CI] 0.01-0.39) and moderate AL (OR 0.14; 95% CI 0.03-0.63), had a lower risk of respiratory allergies compared with subjects with healthy periodontal conditions.Conclusions
The inverse association between periodontitis and respiratory allergies was significant and stronger in patients with type 1 diabetes mellitus than in their previous study among patients who do not have diabetes.